Pryfiber is developing a flexible micro-endoscope using a single multimode optical fiber. The company aims to revolutionise diagnostic and interventional endoscopy by becoming the primary enabler of all precision procedures. The technology will pioneer endoscopy to small spaces – such as joints, winding lumina in cardiac arteries and blood vessels in the brain – where current endoscopes are too big and clinical decision can be compromised.
Endoscopy is widely used for diagnostic and treatment purposes but is a complex procedure. Current endoscopes are too thick and/or inflexible to enter very small spaces like joints or winding lumina such as cardiac arteries and blood vessels in the brain. We are building a hybrid device able to capture microscopic and macroscopic images for diagnosis and treatment.
The Pryfiber single multimode optical fibre (MMF) is a device with only one optical fibre which allows for minimally invasive imaging due to an ultrathin diameter of <300 microns. The core innovation is an AI algorithm that enables real-time calibration of the endoscope during surgical or imaging procedures. The algorithm uses deep learning to reorganise the light that travels through the MMF, recreating accurate and useful images. Furthermore, this technology enables both microscopic high-resolution cellular imaging as well as standard endoscope tissue imaging.